Bharglob 16.5% Injection 2ml

Description
PRODUCT DETAILS
About Bharglob 16.5% Injection 1’s
Bharglob 16.5% Injection 1’s belongs to the class of medications called ‘immunising agents’ used to treat immunoglobulin (antibody) deficiency and certain inflammatory disorders. It is used to treat immunoglobulin deficiency in people with primary immunodeficiency or PID (present from birth) and secondary immunodeficiency or SID (developed in the later stages of life). Bharglob 16.5% Injection 1’s is also used to treat inflammatory disorders such as primary immune thrombocytopenia (reduced number of platelets), Guillain-Barre syndrome (short-term inflammation of the peripheral nerves causing weakness of legs and upper limbs), Kawasaki disease (inflammation of blood vessels in children), chronic inflammatory demyelinating polyneuropathy or CIDP (long-term inflammation of peripheral nerves), and multifocal motor neuropathy (progressive disease leading to weakness of arms and legs).
Bharglob 16.5% Injection 1’s contains ‘Human normal immunoglobulin’, which replaces the deficient antibodies necessary to act against infections and inflammation. It works exactly as the immunoglobulins present in the body. Immunoglobulins are an essential part of the immune system which recognises the antigens or foreign elements in the body and aids in their destruction. It also helps to reduce inflammation by improving immunity.
It would be best if you took Bharglob 16.5% Injection 1’s precisely as prescribed by your doctor. Bharglob 16.5% Injection 1’s may cause side effects such as swelling or hardening at the injection site and headache, pain in the face, back, arms, legs, joints, or neck, fever, flu-like illness (runny nose and sore throat), blisters in the mouth, and throat, and throat tightness. These side effects are usually mild and temporary. However, if any of the side effects persist or get worse, inform your doctor immediately.
It is not recommended to take Bharglob 16.5% Injection 1’s if you are allergic to any of its contents, or have blood clotting disorders. Before taking Bharglob 16.5% Injection 1’s, inform your doctor if you had any vaccinations recently, or have already had this product recently. Bharglob 16.5% Injection 1’s should be used with caution in people with immunoglobulin A (IgA) deficiency (IgA is a type of antibody that protects against infections). Bharglob 16.5% Injection 1’s is probably safe when given to children, pregnant women, and breastfeeding mothers. Bharglob 16.5% Injection 1’s should be used with caution in elderly people. Bharglob 16.5% Injection 1’s may not interact with alcohol. Bharglob 16.5% Injection 1’s may cause dizziness, so do not drive or operate heavy machinery if you feel dizzy.
Uses of Bharglob 16.5% Injection 1’s
Immunoglobulin deficiency and inflammatory disorders such as primary immune thrombocytopenia, Guillain-Barre syndrome, Kawasaki disease, chronic inflammatory demyelinating polyneuropathy, and multifocal motor neuropathy.
Medicinal Benefits
Bharglob 16.5% Injection 1’s acts by replacing the deficient antibodies that are necessary to act against infections and inflammation. It works exactly as the immunoglobulins present in the body. Immunoglobulins are an important part of the immune system which recognizes the antigens or foreign elements in the body and causes their destruction. It is used to treat immunoglobulin deficiency in people with primary immunodeficiency or PID (present from birth) and secondary immunodeficiency or SID (developed in the later stages of life). Bharglob 16.5% Injection 1’s is also used to treat inflammatory disorders such as primary immune thrombocytopenia (reduced number of platelets), Guillain-Barre syndrome (short-term inflammation of the peripheral nerves causing weakness of legs and upper limbs), Kawasaki disease (inflammation of blood vessels in children), chronic inflammatory demyelinating polyneuropathy or CIDP (long-term inflammation of peripheral nerves), and multifocal motor neuropathy (progressive disease leading to weakness of arms and legs).
Directions for Use
Storage
Side Effects of Bharglob 16.5% Injection 1’s
- Swelling or hardening at the injection site
- Headache
- Pain in the face, back, arms, legs, joints, or neck
- Fever
- Flu-like illness (runny nose and sore throat)
- Blisters in the mouth and throat
- Throat tightness
In-Depth Precautions and Warning
Drug Warnings
Bharglob 16.5% Injection 1’s should be used with caution in people with immunoglobulin A (IgA) deficiency (IgA is a type of antibody that protects against infections) as there is an increased risk of allergic reactions. Bharglob 16.5% Injection 1’s may cause a sudden fall in blood pressure with an allergic reaction, including shock, even in patients who have tolerated previous treatment with this medicine. So, it is advised to monitor patients during infusion and at least 20 min after the infusion. If you develop a severe headache, drowsiness, fever, neck stiffness, sensitivity to light, nausea, and vomiting after Bharglob 16.5% Injection 1’s infusion, inform your doctor immediately. It may signify aseptic meningitis syndrome (severe inflammation of the brain’s linings). Bharglob 16.5% Injection 1’s should be used with caution in people with obesity or overweight, diabetes, high blood pressure (hypertension), hypovolemia (low blood volume), and blood clotting disorders, as there is a risk of developing a blood clot (very rare effect of Bharglob 16.5% Injection 1’s). So, inform your doctor if you notice any sign of a blood clot, such as pain, swelling and unusual warmth of a limb, weakness on one side of the body, confusion, sudden shortness of breath, chest pain worsening on deep breathing, and difficulty speaking. Bharglob 16.5% Injection 1’s should be used with caution in patients with kidney problems or who have taken medicines that may harm kidneys (nephrotoxic drugs) as Bharglob 16.5% Injection 1’s may cause problems with kidney function in these people. In rare cases, Bharglob 16.5% Injection 1’s may cause non-cardiogenic pulmonary oedema (accumulation of fluid in the lungs’ air spaces, which is a non-heart related condition). In such cases, patients may experience breathing difficulty, bluish skin, and very low oxygen levels in the blood.
Drug Interactions
Drug-Drug Interactions: Bharglob 16.5% Injection 1’s may interact with loop diuretics (furosemide and ethacrynic acid) and live vaccines (MMR vaccine (measles, mumps, and rubella) and varicella vaccine).
Drug-Food Interactions: No interactions found.
Drug-Disease Interactions: Bharglob 16.5% Injection 1’s should be used with caution in people with blood clotting disorders and immunoglobulin A (IgA) deficiency.
Safety Advice
ALCOHOL
Bharglob 16.5% Injection 1’s may not interact with alcohol. However, limit or avoid consumption of alcohol to avoid possible side effects.
PREGNANCY
Inform your doctor if you are pregnant or intend to become pregnant before receiving Bharglob 16.5% Injection 1’s. Your doctor will assess the benefits and the risks before prescribing.
BREAST FEEDING
Inform your doctor if you are breastfeeding before receiving Bharglob 16.5% Injection 1’s. Your doctor will assess the benefits and the risks before prescribing.
DRIVING
Bharglob 16.5% Injection 1’s may cause dizziness, so do not drive or operate heavy machinery if you feel dizzy after receiving this medicine.
LIVER
Bharglob 16.5% Injection 1’s should be used with caution in patients with liver diseases. Your doctor may adjust the dose if necessary based on your condition.
KIDNEY
Bharglob 16.5% Injection 1’s should be used with caution in patients with kidney diseases. Your doctor may adjust the dose if necessary based on your condition.
Habit Forming
Diet & Lifestyle Advise
- Eat a healthy diet that includes grains, fresh fruits, vegetables, lean meats, and dairy products.
- Stay active and do moderate exercises every day. Maintain a normal weight.
- Get enough sleep, as sleep and immunity are closely related.
- Limit intake of sugar-rich foods or drinks.
- Stay hydrated.
- Practice good hygiene.
- Manage stress levels.
Special Advise
- Bharglob 16.5% Injection 1’s injection should not be given intravenously.
- The side effects can be reduced or sometimes avoided by giving the Bharglob 16.5% Injection 1’s infusion at a slow rate.
- The patient should be observed during the whole infusion and for at least 20 min after giving the Bharglob 16.5% Injection 1’s infusion to exclude any development of the allergic reaction.
- It is strongly recommended that each time a dose of Bharglob 16.5% Injection 1’s is given, the name and batch number of the medicine should be recorded to maintain a record of the batches used.
- Bharglob 16.5% Injection 1’s may alter some blood test results for a certain time, so inform your doctor that you have Bharglob 16.5% Injection 1’s before undergoing blood tests.
- Bharglob 16.5% Injection 1’s should be used with caution in patients with diabetes as it may alter blood sugar levels. Bharglob 16.5% Injection 1’s doesn’t contain sugar; however, it can be diluted in a special sugar solution before giving the infusion.
- Do not take any vaccines (especially live vaccines) at least 3 months after taking Bharglob 16.5% Injection 1’s as this medicine may make the vaccine less effective.
Bharat Serums & Vaccines Ltd
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