A-CN Gel(Topical) 20gm
Description
INTRODUCTION
A CN is a combination of Clindamycin and Nicotinamide which belongs to a group of medicines called Lincomycin antibiotics and Vitamin B3 complex, respectively. A CN is used to treat mild to moderate acne which is a skin condition that occurs when hair follicles become plugged with oil and dead skin cells which may occur due to variety of causes such as genetics, fluctuating hormone levels, stress, high humidity or using oily or greasy personal care products which may affect people of all ages. It is characterized by symptoms such as open or closed plugged pores, small red & tender bumps, pimples, large, solid, or painful lumps under the skin, and painful & pus-filled lumps under the skin.
Clindamycin is a lincomycin antibiotic that reduces free fatty acid concentrations on the skin and suppresses the growth of Propionibacterium acnes (Corynebacterium acnes), a bacteria found in sebaceous glands and follicles. Nicotinamide is a vitamin of B3 complex that exerts anti-inflammatory effect in acne and interrupts sebum production.
Avoid applying A CN, if you are allergic to Clindamycin or Nicotinamide, and or have a history of regional enteritis (inflamed gastrointestinal tract), ulcerative colitis (inflammatory bowel disease), antibiotic associated colitis (inflammation of large intestine), liver or renal impairment. Before applying A CN, inform your doctor if you have eczema (skin inflammation), or asthma.
A CN is not recommended for use during pregnancy and in breastfeeding women, which is also not recommended for use in children and adolescents (below 12 years). Consult your doctor before applying A CN. The most common symptoms of using A CN are skin inflammation, contact dermatitis (red, itchy rash), inflammation of hair follicles, itchy skin, dry skin, peeling of skin and skin redness. Consult your doctor if any of these symptoms worsen.
USES OF A CN
- Treats mild to moderate acne
HOW A CN WORKS
A CN helps to treat acne, where clindamycin reduces free fatty acid concentrations on the skin and suppresses the growth of Propionibacterium acnes (Corynebacterium acnes), a bacteria found in sebaceous glands and follicles, and nicotinamide exerts anti-inflammatory effect in acne and interrupts sebum production.
DIRECTIONS FOR USE
Apply A CN as advised by your physician. It is for external use only. Before applying the medicine normally wash and dry the affected area and apply a thin layer of this medicine on the affected area. Treated areas on the face need not be covered with a plaster or bandage. Do not apply A CN on your face beyond the recommended duration. Avoid applying A CN around your eyes, including eyelids. Rinse it off with water if you accidentally get it in these areas.
SIDE EFFECTS OF A CN
COMMON
- Skin inflammation
- Contact dermatitis (red, itchy rash)
- Dermatitis fungal (scaly and itchy rash or discoloration of skin caused by fungal infection)
- Inflammation of hair follicles
- Signs of photosensitivity reactions such as rash, blisters and red bumps
- Itching skin
- Skin redness
- Dry skin
- Peeling of skin
UNCOMMON
- Skin irritation
RARE
- Signs of allergic reactions such as itching, redness, swelling or burning sensations can occur
Stop applying A CN and contact your doctor if you experience any of the following side effects:
- Diarrhoea
HOW TO MANAGE SIDE EFFECTS
Dry Skin:
Try moisturizing your skin with an ointment, cream, or lotion 2 or 3 times a day, or as more often as needed. Moisturizers help to keep the area moisture, so they work best on damp skin. After you bathe, pat your skin dry then apply your moisturizer. Consult your before using any moisturizer. Try to avoid using skin care products and soaps that contain alcohol, fragrances, dyes, or other chemicals.
Diarrhoea:
Drink lots of fluids, such as water to keep yourself hydrated. Try to avoid taking any medicine on your own to treat diarrhea and consult your doctor if the symptom gets worse.
WARNING & PRECAUTIONS
PREGNANCY
A CN is not recommended for use during pregnancy. Consult your doctor before applying A CN.
BREASTFEEDING
A CN is not recommended for use in breastfeeding women. Consult your doctor before applying A CN.
DRIVING AND USING MACHINES
A CN should not affect your ability to drive or operate machines. Consult your doctor before applying A CN.
KIDNEY
A CN is not recommended for use in patients having kidney disease such as kidney impairment. It should be used with caution in patients having other kidney diseases. Consult your doctor before applying A CN.
LIVER
A CN is not recommended for use in patients having liver disease such as liver impairment. It should be used with caution in patients having other liver diseases. Consult your doctor before applying A CN.
ALLERGY
Do not use A CN if you are allergic to Clindamycin or Nicotinamide or any other ingredients of this medicine.
LUNGS
A CN should be used with caution in patients having asthma. Consult your doctor before applying A CN.
OTHERS
A CN is not recommended for use if you have:
- History of regional enteritis (inflamed gastrointestinal tract)
- History of ulcerative colitis (inflammatory bowel disease)
- History of antibiotic associated colitis (inflammation of large intestine)
Before applying A CN, inform your doctor if you have:
- Eczema (skin inflammation)
Use in Pediatrics:
A CN is not recommended for use in children and adolescents (below 12 years). Consult your doctor before applying A CN.
Use in Geriatrics:
A CN should be used with caution in elderly patients (aged 65 years or above). Consult your doctor before applying A CN.
INTERACTIONS
A. Drug – Drug interactions:
Before using A CN, inform your doctor if you are taking any of the following medicines:
- Neuromuscular blocking agents (used adjunctively with anesthesia to produce paralysis) Ex. cisatracurium, vecuronium
- Birth control pills (used to prevent pregnancy) Ex. conjugated estrogen
Overdosage:
If you or anyone else accidentally applies too much of A CN, consult your doctor immediately or visit the nearby hospital. Symptoms of overdosage are diarrhea, bloody diarrhea, and colitis including pseudomembranous colitis (swelling or inflammation of the large intestine that occurs after antibiotic use).
MORE INFORMATION
- Keep A CN out of reach of children
- Store below 25 °C
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